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Xylitylglucoside

Sugar moisturizer from birch — xylitylglucoside (Aquaxyl) combined with xylitol and glucose stimulates the synthesis of NMF components and dermal polysaccharides. Unique mechanism: not just attracts water, but activates the skin's own production of moisturizing factors.

AquaxylNMFHydrationDermal polysaccharides

✓ Safe

Comedogenic Rating

0/5

Irritation Potential

0/5

What is it?

Xylitylglucoside (INCI) — O-β-D-glucopyranosyl-xylitol, synthetic glucoside. Trademark Aquaxyl® (Seppic) — a mixture of xylitylglucoside, anhydroxylitol, and xylitol. Mechanism: stimulates moisture transporters (aquaporins AQP3) in keratinocytes, activates the synthesis of NMF components (amino acids, PCA, lactic acid) and dermal polysaccharides (hyaluronic acid, dermatan sulfate). Also forms a protective film on the surface.

Moisturizing component in essences, creams, and products for dry skin. Popular in Korean-Japanese cosmetics. Often combined with HA, PGA for maximum hydration.

Key Benefits

✦

Activation of aquaporins and moisture transport

Stimulates the expression of AQP3 (aquaporin-3) in keratinocytes — membrane channels for the transport of water and glycerin. Increased AQP3 levels improve moisture distribution in the epidermis. In vitro: +34% expression of AQP3 after treatment with Aquaxyl. Result — better hydration of the deeper layers of the epidermis.

◈

Stimulation of NMF and dermal polysaccharide synthesis

Activates the synthesis of Natural Moisturizing Factor components in keratinocytes. Simultaneously stimulates HA and dermatan sulfate in fibroblasts — dermal hydration. Double effect: epidermal NMF + dermal polysaccharides — hydration at all levels.

✧

Long-lasting hydration and protection from TEWL

Aquaxyl forms a protective film-forming layer that reduces TEWL. Clinical study by Seppic: 8 weeks of 2% Aquaxyl cream — +23% hydration of the stratum corneum, -18% TEWL. The moisturizing effect lasts longer than with the use of simple glycerin.

Suitable for

Dry skinDehydrated skinNormal skinAll skin types

Main Actions

✓ Activation of aquaporins✓ Stimulation of NMF✓ Long-lasting hydration

Aquaxyl = Xylitylglucoside?

Aquaxyl — the trade name of the complex: xylitylglucoside + anhydroxylitol + xylitol (in a ratio of 60:20:20). In INCI, each component is listed separately. If all three are present in the composition — you have Aquaxyl. Xylitylglucoside is the key (main) component of this complex.

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