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Methylpropanediol

A powerful active ingredient carrier — methylpropanediol (MPD) is particularly valued for its ability to significantly enhance the penetration of active components through the stratum corneum. It is often found in concentrated serums with retinol, peptides, and AHA acids.

active ingredient carriersolventpenetration enhancermoisturizer

✓ Safe

Comedogenic Rating

0/5

Irritation Potential

0/5

What is it?

Methylpropanediol (2-methyl-1,3-propanediol, MPD) is a synthetic diol. In INCI: Methylpropanediol. Structurally similar to butylene glycol and propylene glycol, but with a more pronounced penetration-enhancing profile. A colorless, odorless liquid with low viscosity. It effectively dissolves both polar and moderately non-polar actives.

A carrier and solvent in concentrated serums and treatment formulas. Particularly effective in combination with retinol, AHA/BHA, vitamin C, and peptides — it enhances their bioavailability and effectiveness. It is also used as a sensory modifier.

Key Benefits

✦

Maximum active ingredient penetration

MPD is one of the strongest penetration enhancers among glycols. It temporarily increases the permeability of the stratum corneum, allowing a greater amount of active molecules to reach the target layer. The effect is particularly pronounced for retinol and AHA.

◈

Exceptional dissolving ability

Dissolves a wide range of actives — from hydrophilic (niacinamide, hyaluronic acid) to moderately lipophilic (retinol, BHA). Allows the formation of stable high-load concentrates without separation.

✧

Gentle hydration and light texture

As a humectant — it retains water and reduces TEWL. As a sensory modifier — it gives formulations a light, water-like feel without stickiness and residue. Effectively 'thins out' heavy concentrates without losing stability.

Suitable for

for all skin typesfor oily skinfor acne-prone skin

Main Actions

✓ active ingredient penetration✓ active ingredient dissolution✓ hydration✓ light texture

Strong enhancer = increased irritation

MPD enhances the penetration of ALL components, including potentially irritating ones. Serums with MPD + retinol or MPD + AHA can be more aggressive for sensitive skin. Start with a patch test and infrequent use, especially if the skin is reactive.

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