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Soothing

Dipotassium Glycyrrhizate

Soothing active from licorice root — dipotassium glycyrrhizate is the potassium salt of glycyrrhizic acid with pronounced anti-inflammatory and anti-redness effects. One of the most effective natural soothing components in cosmetics for sensitive skin.

Anti-inflammatorySoothinganti-rednessLicorice
✓ Safe
Comedogenic Rating
0/5
Irritation Potential
0/5

What is it?

Dipotassium Glycyrrhizate — potassium salt of glycyrrhizic acid (triterpene saponin from the root of Glycyrrhiza glabra). In INCI: Dipotassium Glycyrrhizate. The water-soluble form is better for aqueous formulations than licorice root extract. It inhibits the activity of 11β-hydroxysteroid dehydrogenase — a mechanism similar to the cortisone-like effect, but without hormonal side effects.

Anti-inflammatory and soothing active in toners, serums, and creams for sensitive, reactive, and rosacea-prone skin. Often used in post-procedure products and products for atopic skin.

Key Benefits

✦
Powerful anti-inflammatory action without steroids
Inhibits the conversion of cortisol to cortisone through the inhibition of 11β-HSD — enhances local anti-inflammatory effect without systemic consequences. Comparable effectiveness to hydrocortisone 0.5% for redness and itching.
◈
Quick reduction of redness and anti-redness
One of the fastest natural anti-redness agents — visible effect within 15–30 minutes after application. Effective for redness from irritation, rosacea triggers, and reactions to active ingredients.
✧
Recovery after procedures
Standard component of post-peel and post-laser products — reduces reactivity, accelerates barrier recovery, and decreases post-inflammatory redness after peels and microneedling.

Suitable for

Sensitive skinSkin with rosaceaReactive skinSkin after procedures

Main Actions

✓ Anti-inflammatory action✓ anti-redness✓ Soothing✓ Barrier recovery
CategorySoothing Ingredients

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